Description
CJC-1295 without DAC 5mg — modified GHRH analogue for research
CJC-1295 without DAC, also written as mod-GRF(1-29), is supplied as lyophilized powder at 99%+ purity for laboratory research on GHRH receptor signaling. The 5mg vial is a pilot or single-arm quantity.
Ships from within the USA. Supplied for laboratory research use only, and not for human or veterinary use.
About CJC-1295 (No DAC) 5mg
This peptide is a 29-residue GHRH analogue carrying four amino acid substitutions that slow enzymatic degradation relative to native GHRH(1-29). The DAC-free form has no drug affinity complex attached, so its behavior in an assay is short-lived compared with the DAC-modified version — which is exactly why researchers use it when a defined, transient stimulus is wanted rather than a sustained one.
Purity by reverse-phase HPLC, identity by mass spectrometry. Naming around this compound is inconsistent across suppliers and papers; the sequence and mass on the specification table below are the authoritative description of what is in the vial.
Research applications of CJC-1295 (No DAC) 5mg
- GHRH receptor concentration–response work in vitro
- cAMP accumulation studies in pituitary-derived cell lines
- Comparative pharmacology against DAC-modified analogues
- Peptide stability and enzymatic degradation research
- Convergent signaling studies alongside ghrelin receptor agonists
How this vial is supplied and handled
The vial arrives as a lyophilized cake or film in a sealed, stoppered vial. Keep it sealed and frozen at -20 °C until the day it is opened; brief periods at ambient temperature in transit are expected and do not compromise dry powder. Let the vial reach room temperature before breaking the seal so atmospheric moisture does not condense onto the cake.
Reconstitute by running the diluent slowly down the inside wall of the vial rather than onto the powder, and swirl rather than shake — peptides denature at an air-liquid interface. Hold the solution at 2–8 °C for short-term use, or aliquot and freeze for longer, and avoid repeated freeze-thaw cycles, the most common cause of a quiet loss of activity between one experiment and the next.
Ordering CJC-1295 (NO DAC) 5mg in the United States
CJC-1295 (NO DAC) 5mg ships to research laboratories throughout the USA, dispatched domestically from our US facility. Every parcel is tracked, and because the material stays inside the country there is no customs entry, no broker fee and no border hold between our shelf and your bench.
Shipping is calculated at checkout and orders over $200 USD ship free anywhere in the United States. Bulk pricing is available on larger quantities — email us before checkout and we will quote it.
Purity guarantee
If an independent laboratory tests this material and reports purity below the figure stated on its certificate, we refund the order and reimburse what the test cost you. Send the lot number printed on the vial along with the third-party report and we will settle it without argument.
The guarantee covers the analysis, not the outcome of your work. What CJC-1295 (No DAC) 5mg does in your model is your experiment; what is in the vial is our responsibility.
Research use only
CJC-1295 (No DAC) 5mg is supplied strictly for laboratory research carried out by qualified professionals. It is not a drug, a dietary supplement or a medical device.
It has not been evaluated or approved by the U.S. Food and Drug Administration for any use. It is not for human or veterinary consumption, for clinical investigation in human subjects, or for therapeutic, diagnostic or cosmetic application of any kind.
We do not provide dosing, administration or protocol advice, and we cannot answer questions about use in people or animals. By ordering, you confirm that you are acquiring this material for lawful research in a controlled laboratory setting and that you will not redistribute it for any other purpose.
Compound identity and specification
Identity data for CJC-1295 without DAC (Mod GRF 1-29), published so the material can be checked against an independent record rather than taken on trust. The formula, mass and registry number below are verified against PubChem and can be looked up directly.
| Compound | CJC-1295 without DAC (Mod GRF 1-29) |
|---|---|
| Sequence | [D-Ala2, Gln8, Ala15, Leu27]-GRF(1-29) amide |
| Molecular formula | C152H252N44O42 |
| Molecular mass | 3367.9 g/mol |
| CAS registry number | 863288-34-0 |
| PubChem | CID 56841945 |
| Vial content | 5 mg |
| Physical form | Lyophilized powder in a sealed vial |
| Analysis | Third-party HPLC where a report has been commissioned; see the certificates of analysis page |
| Supplied for | Laboratory research use only |
Analytical note — CJC-1295 without DAC (Mod GRF 1-29). This is the version without the drug-affinity complex. CJC-1295 with DAC is a different molecule, C165H269N47O46 at about 3,647 g/mol, CAS 446262-90-4 – a difference of roughly 280 Da. The two are the most commonly confused pair in this category, and the mass on the certificate is what separates them.
Identity references The molecular formula, molecular mass and CAS registry number above are taken from the PubChem record linked in the table, not from a supplier datasheet, so every figure can be checked against an independent source in one click. Sequences are given as reported in the peptide literature, in the one-letter or three-letter convention as appropriate, with any non-standard residue named in full. Where a compound exists in more than one form — a free peptide and a metal complex, a fragment and its parent protein, a modified and an unmodified analog — the form supplied is the one identified here, and the mass on the certificate of analysis is what distinguishes it.
Research Literature
Peer-reviewed studies involving this compound and its class. All findings listed are from in vitro, cell culture or animal models and are provided for scientific reference only. This product is supplied for laboratory research and is not approved for human consumption, clinical, or veterinary use.
- Jette L, et al. Endocrinology. 2005;146(7):3052-3058. In cultured rat anterior pituitary cells and Sprague-Dawley rats, measured GH secretion, Cys34-albumin conjugate formation and resistance to DPP-IV cleavage. Source · PMID 15817669
- Alba M, et al. Am J Physiol Endocrinol Metab. 2006;291(6):E1290-E1294. In GHRH-knockout mice, measured pituitary GH and IGF-I expression. Source · PMID 16822960
Every certificate of analysis we hold is collected on the certificates of analysis page. Where a lot has not been independently tested we do not claim that it has.
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