Description
Tesamorelin 10mg — stabilized GHRH analogue for research
Tesamorelin 10mg is a synthetic GHRH analogue supplied as lyophilized powder for laboratory research on growth hormone-releasing hormone receptor signaling.
Ships from within the USA. Supplied for laboratory research use only, and not for human or veterinary use.
About Tesamorelin 10mg
Tesamorelin is GHRH(1-44) carrying an N-terminal trans-3-hexenoyl modification. The acyl group slows degradation by dipeptidyl peptidase, so in an in vitro system the peptide persists substantially longer than the native sequence. For a laboratory, that makes it a useful member of a comparison set: native GHRH(1-29), a substituted analogue, and an N-acylated analogue give three points on a stability axis while engaging the same receptor.
Purity by reverse-phase HPLC, identity by mass spectrometry. The N-terminal modification is part of the identity data on the specification table below.
Research applications of Tesamorelin 10mg
- GHRH receptor pharmacology with an enzymatically stabilized ligand
- Comparative degradation kinetics against native and substituted analogues
- cAMP accumulation studies in pituitary-derived cell lines
- Structure–stability relationship research on N-acylated peptides
- Assay work requiring a long-persisting receptor stimulus
How this vial is supplied and handled
The vial arrives as a lyophilized cake or film in a sealed, stoppered vial. Keep it sealed and frozen at -20 °C until the day it is opened; brief periods at ambient temperature in transit are expected and do not compromise dry powder. Let the vial reach room temperature before breaking the seal so atmospheric moisture does not condense onto the cake.
Reconstitute by running the diluent slowly down the inside wall of the vial rather than onto the powder, and swirl rather than shake — peptides denature at an air-liquid interface. Hold the solution at 2–8 °C for short-term use, or aliquot and freeze for longer, and avoid repeated freeze-thaw cycles, the most common cause of a quiet loss of activity between one experiment and the next.
Ordering TESAMORELIN 10mg in the United States
TESAMORELIN 10mg ships to research laboratories throughout the USA, dispatched domestically from our US facility. Every parcel is tracked, and because the material stays inside the country there is no customs entry, no broker fee and no border hold between our shelf and your bench.
Shipping is calculated at checkout and orders over $200 USD ship free anywhere in the United States. Bulk pricing is available on larger quantities — email us before checkout and we will quote it.
Purity guarantee
If an independent laboratory tests this material and reports purity below the figure stated on its certificate, we refund the order and reimburse what the test cost you. Send the lot number printed on the vial along with the third-party report and we will settle it without argument.
The guarantee covers the analysis, not the outcome of your work. What Tesamorelin 10mg does in your model is your experiment; what is in the vial is our responsibility.
Research use only
Tesamorelin 10mg is supplied strictly for laboratory research carried out by qualified professionals. It is not a drug, a dietary supplement or a medical device.
It has not been evaluated or approved by the U.S. Food and Drug Administration for any use. It is not for human or veterinary consumption, for clinical investigation in human subjects, or for therapeutic, diagnostic or cosmetic application of any kind.
We do not provide dosing, administration or protocol advice, and we cannot answer questions about use in people or animals. By ordering, you confirm that you are acquiring this material for lawful research in a controlled laboratory setting and that you will not redistribute it for any other purpose.
Compound identity and specification
Identity data for Tesamorelin, published so the material can be checked against an independent record rather than taken on trust. The formula, mass and registry number below are verified against PubChem and can be looked up directly.
| Compound | Tesamorelin |
|---|---|
| Sequence | trans-3-hexenoyl-GRF(1-44) amide |
| Molecular formula | C221H366N72O67S |
| Molecular mass | 5136 g/mol |
| CAS registry number | 218949-48-5 |
| PubChem | CID 16137828 |
| Vial content | 10 mg |
| Physical form | Lyophilized powder in a sealed vial |
| Analysis | Third-party HPLC where a report has been commissioned; see the certificates of analysis page |
| Supplied for | Laboratory research use only |
Analytical note — Tesamorelin. At 44 residues plus an N-terminal hexenoyl group this is the largest molecule in the catalog, and the acyl group is the point: it is what distinguishes tesamorelin from unmodified GRF(1-44). On a 5,136 g/mol parent, single-residue deletions are a sub-1% mass shift, so purity here depends on chromatographic resolution more than on mass alone.
Identity references The molecular formula, molecular mass and CAS registry number above are taken from the PubChem record linked in the table, not from a supplier datasheet, so every figure can be checked against an independent source in one click. Sequences are given as reported in the peptide literature, in the one-letter or three-letter convention as appropriate, with any non-standard residue named in full. Where a compound exists in more than one form — a free peptide and a metal complex, a fragment and its parent protein, a modified and an unmodified analog — the form supplied is the one identified here, and the mass on the certificate of analysis is what distinguishes it.
Research Literature
Peer-reviewed studies involving this compound and its class. All findings listed are from in vitro, cell culture or animal models and are provided for scientific reference only. This product is supplied for laboratory research and is not approved for human consumption, clinical, or veterinary use.
- Ferdinandi ES, et al. Basic Clin Pharmacol Toxicol. 2007;100(1):49-58. In rats, dogs and pigs, measured enzymatic stability of the trans-3-hexenoyl modification, plasma elimination kinetics and plasma IGF-1 response. Source · PMID 17214611
Literature notes: Preclinical literature for this compound is limited; most published work reports clinical endpoints and is outside the scope of this reference list.
Every certificate of analysis we hold is collected on the certificates of analysis page. Where a lot has not been independently tested we do not claim that it has.
Related Research Compounds
Browse more compounds in GHS, or view the full research peptide catalog.
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