DSIP Peptide 5mg

Description

DSIP peptide 5mg — delta sleep-inducing peptide for laboratory research

DSIP peptide 5mg is a synthetic nonapeptide supplied as lyophilized powder at 99%+ purity for laboratory research. The name is historical, taken from the context in which the sequence was first isolated, and should not be read as a description of what the compound does in any system.

Ships from within the USA. Supplied for laboratory research use only, and not for human or veterinary use.

About DSIP 5mg

DSIP is a nine-residue peptide first isolated from rabbit cerebral venous blood in the 1970s. It is an unusual compound to work with: the early reports have proved difficult to replicate consistently, no receptor has been definitively identified for it, and the mechanistic literature remains thin. That makes it a legitimate subject for laboratory investigation and a poor subject for confident claims, and we are not going to make any.

Purity by reverse-phase HPLC, identity by mass spectrometry. What is in the vial is well characterized; what it does is an open research question.

Research applications of DSIP 5mg

• Neuropeptide binding and receptor identification studies
• Electrophysiological work in brain slice preparations
• Comparative neuropeptide screening in vitro
• Peptide stability and plasma degradation research
• Rodent protocols conducted under institutional approval

How this vial is supplied and handled

The vial arrives as a lyophilized cake or film in a sealed, stoppered vial. Keep it sealed and frozen at -20 °C until the day it is opened; brief periods at ambient temperature in transit are expected and do not compromise dry powder. Let the vial reach room temperature before breaking the seal so atmospheric moisture does not condense onto the cake.

Reconstitute by running the diluent slowly down the inside wall of the vial rather than onto the powder, and swirl rather than shake — peptides denature at an air-liquid interface. Hold the solution at 2–8 °C for short-term use, or aliquot and freeze for longer, and avoid repeated freeze-thaw cycles, the most common cause of a quiet loss of activity between one experiment and the next.

Ordering DSIP 5mg in the United States

DSIP 5mg ships to research laboratories throughout the USA, dispatched domestically from our US facility. Every parcel is tracked, and because the material stays inside the country there is no customs entry, no broker fee and no border hold between our shelf and your bench.

Shipping is calculated at checkout and orders over $200 USD ship free anywhere in the United States. Bulk pricing is available on larger quantities — email us before checkout and we will quote it.

Purity guarantee

If an independent laboratory tests this material and reports purity below the figure stated on its certificate, we refund the order and reimburse what the test cost you. Send the lot number printed on the vial along with the third-party report and we will settle it without argument.

The guarantee covers the analysis, not the outcome of your work. What DSIP 5mg does in your model is your experiment; what is in the vial is our responsibility.

Research use only

DSIP 5mg is supplied strictly for laboratory research carried out by qualified professionals. It is not a drug, a dietary supplement or a medical device.

It has not been evaluated or approved by the U.S. Food and Drug Administration for any use. It is not for human or veterinary consumption, for clinical investigation in human subjects, or for therapeutic, diagnostic or cosmetic application of any kind.

We do not provide dosing, administration or protocol advice, and we cannot answer questions about use in people or animals. By ordering, you confirm that you are acquiring this material for lawful research in a controlled laboratory setting and that you will not redistribute it for any other purpose.

Compound identity and specification

Identity data for DSIP, published so the material can be checked against an independent record rather than taken on trust. The formula, mass and registry number below are verified against PubChem and can be looked up directly.

Analytical note — DSIP. Nine residues, two of them acidic, and a single tryptophan. That tryptophan is the analytical handle: it gives a 280 nm signal, and oxidised tryptophan adds 16 Da and typically resolves as a distinct earlier peak.

Identity references The molecular formula, molecular mass and CAS registry number above are taken from the PubChem record linked in the table, not from a supplier datasheet, so every figure can be checked against an independent source in one click. Sequences are given as reported in the peptide literature, in the one-letter or three-letter convention as appropriate, with any non-standard residue named in full. Where a compound exists in more than one form — a free peptide and a metal complex, a fragment and its parent protein, a modified and an unmodified analog — the form supplied is the one identified here, and the mass on the certificate of analysis is what distinguishes it.

Research Literature

Peer-reviewed studies involving this compound and its class. All findings listed are from in vitro, cell culture or animal models and are provided for scientific reference only. This product is supplied for laboratory research and is not approved for human consumption, clinical, or veterinary use.

• Nakamura A, et al. J Neurochem. 1991;57(3):1013-1018. In rat medullary and regional brain synaptosomes, measured calcium-dependent, tetrodotoxin-insensitive Met-enkephalin release and calcium uptake. Source · PMID 1861139
• Nakamura A, et al. Neuropeptides. 1993;24(3):131-138. In rat brain synaptosome preparations, measured depolarisation-evoked release and aminopeptidase-mediated degradation. Source · PMID 8474631
• Iyer KS, McCann SM Neuroendocrinology. 46(1):93-95. In rat median eminence tissue in vitro, measured dose-dependent inhibition of somatostatin release, blocked by the dopamine antagonist pimozide. Source · PMID 2886936

Literature notes: The publication year for Iyer and McCann is recorded inconsistently across indexes; the identifiers are confirmed.

Every certificate of analysis we hold is collected on the certificates of analysis page. Where a lot has not been independently tested we do not claim that it has.

Related Research Compounds

Browse more compounds in Neuropeptides, or view the full research peptide catalog.

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