Description
Semax 10mg — ACTH(4-10) analogue research peptide
Semax 10mg is a synthetic analogue of the ACTH(4-10) fragment, supplied as lyophilized powder at 99%+ purity for neuroscience-oriented laboratory research.
Ships from within the USA. Supplied for laboratory research use only, and not for human or veterinary use.
About Semax 10mg
Semax is the ACTH(4-10) heptapeptide extended at the C-terminus with proline-glycine-proline. The parent fragment is a melanocortin-derived sequence without corticotropic activity, and the extension slows its degradation, giving a tool compound stable enough for in vitro and rodent work.
Published laboratory research centers on BDNF and TrkB expression in cultured neurons and in rodent brain tissue, on monoamine turnover, and on gene expression profiling after administration in animal models. As with other proline-terminated peptides, chromatographic peak broadening is expected and is a property of the sequence.
Research applications of Semax 10mg
- BDNF and TrkB expression studies in neuronal culture
- Monoamine turnover measurements in brain tissue
- Transcriptional profiling in rodent models under institutional approval
- Comparative work against ACTH fragments and related analogues
- Peptide stability and enzymatic degradation research
How this vial is supplied and handled
The vial arrives as a lyophilized cake or film in a sealed, stoppered vial. Keep it sealed and frozen at -20 °C until the day it is opened; brief periods at ambient temperature in transit are expected and do not compromise dry powder. Let the vial reach room temperature before breaking the seal so atmospheric moisture does not condense onto the cake.
Reconstitute by running the diluent slowly down the inside wall of the vial rather than onto the powder, and swirl rather than shake — peptides denature at an air-liquid interface. Hold the solution at 2–8 °C for short-term use, or aliquot and freeze for longer, and avoid repeated freeze-thaw cycles, the most common cause of a quiet loss of activity between one experiment and the next.
Ordering SEMAX 10mg in the United States
SEMAX 10mg ships to research laboratories throughout the USA, dispatched domestically from our US facility. Every parcel is tracked, and because the material stays inside the country there is no customs entry, no broker fee and no border hold between our shelf and your bench.
Shipping is calculated at checkout and orders over $200 USD ship free anywhere in the United States. Bulk pricing is available on larger quantities — email us before checkout and we will quote it.
Purity guarantee
If an independent laboratory tests this material and reports purity below the figure stated on its certificate, we refund the order and reimburse what the test cost you. Send the lot number printed on the vial along with the third-party report and we will settle it without argument.
The guarantee covers the analysis, not the outcome of your work. What Semax 10mg does in your model is your experiment; what is in the vial is our responsibility.
Research use only
Semax 10mg is supplied strictly for laboratory research carried out by qualified professionals. It is not a drug, a dietary supplement or a medical device.
It has not been evaluated or approved by the U.S. Food and Drug Administration for any use. It is not for human or veterinary consumption, for clinical investigation in human subjects, or for therapeutic, diagnostic or cosmetic application of any kind.
We do not provide dosing, administration or protocol advice, and we cannot answer questions about use in people or animals. By ordering, you confirm that you are acquiring this material for lawful research in a controlled laboratory setting and that you will not redistribute it for any other purpose.
Compound identity and specification
Identity data for Semax, published so the material can be checked against an independent record rather than taken on trust. The formula, mass and registry number below are verified against PubChem and can be looked up directly.
| Compound | Semax |
|---|---|
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP) |
| Molecular formula | C37H51N9O10S |
| Molecular mass | 813.9 g/mol |
| CAS registry number | 80714-61-0 |
| PubChem | CID 9811102 |
| Vial content | 10 mg |
| Physical form | Lyophilized powder in a sealed vial |
| Analysis | Third-party HPLC where a report has been commissioned; see the certificates of analysis page |
| Supplied for | Laboratory research use only |
Analytical note — Semax. The N-terminal methionine is among the most oxidation-prone residues in the standard set. Methionine sulfoxide adds 16 Da and usually elutes earlier than the parent peak, so a competent analysis separates it rather than integrating it into the main peak.
Every certificate of analysis we hold is collected on the certificates of analysis page. Where a lot has not been independently tested we do not claim that it has.
Related Research Compounds
Browse more compounds in Neuropeptides, or view the full research peptide catalog.




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